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PT-141

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Description

PT-141Research Use Only (RUO): PT 141 peptide (Bremelanotide) is supplied exclusively for in vitro and non clinical laboratory research. Not for human or veterinary use, not for injection, not for consumption. PT 141 Peptide (Bremelanotide) Research Use Only (RUO) Overview PT 141, commonly referenced as bremelanotide peptide, is a synthetic melanocortin receptor agonist used in controlled research workflows to investigate receptor mediated signaling and

⚠ Research Use Only (RUO): PT-141 peptide (Bremelanotide) is supplied exclusively for in-vitro and non-clinical laboratory research. Not for human or veterinary use, not for injection, not for consumption.

PT-141 Peptide (Bremelanotide) — Research Use Only (RUO) Overview

PT-141, commonly referenced as bremelanotide peptide, is a synthetic melanocortin receptor agonist used in controlled research workflows to investigate receptor-mediated signaling and downstream pathway readouts in non-clinical models. This page provides laboratory context only and does not imply clinical outcomes.

PT-141 (Bremelanotide) Specifications — CAS 189691-06-3, ≥99% HPLC

Product Name PT-141 (Bremelanotide)
CAS Number 189691-06-3
Molecular Formula C50H68N14O10
Molecular Weight ~1025.2 g/mol
Peptide Type Cyclic melanocortin receptor research peptide
Purity ≥99% (HPLC verified)
Verification HPLC / MS tested (batch-based)
Physical Form Lyophilized powder
Documentation CoA available upon request
Grade Research Use Only (RUO)

PT-141 Keywords Embedded for Search Intent (USA)

Common queries include pt-141 peptide, bremelanotide, pt-141 bremelanotide, melanocortin receptor agonist, MC4R, MC3R, pt-141 lyophilized powder, pt-141 storage, and pt-141 reconstitution.

Below, those terms are addressed naturally through RUO-safe technical sections and FAQs (no medical claims).

What Is PT-141 (Bremelanotide)? Melanocortin Receptor Research Peptide

In research literature, bremelanotide (PT-141) is discussed as a melanocortin-pathway probe, often evaluated for activity across melanocortin receptor subtypes (commonly referenced in CNS signaling models). Researchers use PT-141 to explore receptor binding, cAMP signaling, and pathway-level modulation under defined experimental conditions.

PT-141 Mechanism of Action in MC4R / MC3R Signaling Models (Research Context)

PT-141 is widely referenced for melanocortin receptor pathway investigation, supporting assays that quantify receptor activation and downstream signaling readouts (e.g., cAMP-linked responses) in controlled in-vitro systems. Experimental design, receptor subtype selection, and endpoints are protocol-dependent.

PT-141 Research Applications: Receptor Binding, CNS Pathways, and Autonomic Readouts

  • Melanocortin receptor binding assays: receptor affinity/activation profiling in cell systems
  • MC4R pathway mapping: downstream signaling cascade exploration in mechanistic workflows
  • Neuroscience models: CNS-linked pathway studies focused on signaling and regulatory circuits
  • Comparative peptide research: contrast vs. other melanocortin-pathway peptides (protocol-dependent)
  • Analytical/QC workflows: identity/purity checks and reproducibility tracking in lab environments

PT-141 Storage and Handling: Lyophilized Peptide Powder + Reconstitution (RUO)

For pt-141 storage and preparation in RUO workflows, follow your laboratory SOP and the product documentation. Many labs store lyophilized peptides cold, protected from light and moisture, and prepare solutions only as needed for assays.

  • Lyophilized PT-141: store at −20°C or below, protected from light/moisture
  • After preparation: use within your protocol stability window (solvent/time are assay-dependent)
  • Best practice: aliquot where appropriate; avoid repeated freeze–thaw cycles

Why Researchers Choose Peptides Skin for PT-141 (Bremelanotide) RUO Supply

  • Verified purity: ≥99% HPLC verified (batch-based)
  • Identity support: MS testing and traceability practices
  • CoA availability: documentation for qualified research buyers
  • Secure shipping: packaging optimized for stability during transit

FAQs — PT-141 Peptide (Bremelanotide) Research Use Only

What is PT-141 peptide (bremelanotide) in research?

PT-141 (bremelanotide) is a melanocortin-pathway research peptide used in non-clinical workflows to study receptor signaling (e.g., MC4R/MC3R) and downstream mechanistic readouts in controlled systems.

Is PT-141 from Peptides Skin approved for human use?

No. Peptides Skin supplies PT-141 strictly as Research Use Only (RUO). It is not intended or approved for human or veterinary use, injection, or consumption.

What are the CAS number and molecular weight of PT-141?

Common references list CAS 189691-06-3 and a molecular weight of approximately ~1025.2 g/mol for bremelanotide (PT-141). Always verify against batch documentation for your laboratory records.

How should PT-141 lyophilized powder be stored?

Store lyophilized PT-141 at −20°C or below, protected from light and moisture. Follow your SOP and minimize freeze–thaw cycles to reduce experimental variability.

Do you provide PT-141 CoA and HPLC/MS data?

Yes. CoA is available upon request, with batch-based HPLC purity verification and MS identity support for qualified research customers.

WARNING — Research Use Only (RUO):
For laboratory research and development purposes only. Not for human or veterinary use, injection, or consumption. Not intended to diagnose, treat, cure, or prevent any disease. Any mention of mechanisms refers exclusively to controlled research models.
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M Weidner
Dallas, US
★★★★★ 3
Liked it
Format: Kindle
I liked the worlds and the characters. The prophesy is confusing in that I would think, since all worlds ore on a path to destruction, the angels would want their world to be saved. I am sure there is more evil that will be revealed as the series proceeds. I dislike a prolonged “poor little me” trope and the main character has moved past that, thankfully, and began to show a fierce attitude as the novel progressed. The last portion of the novel had some great action. It’s worth reading, just be patient with a slow start.
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Reviewed in the United States on February 14, 2024
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Darcie Reads A Lot
Lexington, US
★★★★★ 5
Unexpectedly emotional and packed with action!
Format: Kindle
Why do I suddenly want nothing more than a tiny wyvern to snuggle with?! It’s adorable and I absolutely love all of those moments! Wings of Stars was everything I’ve come expect from this powerful author duo. The fact that it’s written by two different people is completely transparent to the reader and they’ve brought us another world and characters that we’re all emotionally connected to and fully invested in! The injustice that we see from Alfemir in the many forms in which it comes is infuriating and makes me desperate for the conclusion of the story so they can all get what’s coming to them! I love all the guys right now, with one exception, and if you’re read it, you know exactly who I’m talking about. Bastian is hilarious - he was the comedic relief through an otherwise quite serious story. My heart bleeds for him and I can’t wait to see how he progresses through the series. Parts of Wings of Stars were unexpectedly emotional and of course I was left with my jaw on the floor at that cliffhanger! Next, please!
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Reviewed in the United States on October 18, 2025
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josh portwood
Natrona Heights, US
★★★★★ 5
Niz !!!
Format: Kindle
First, let me say that I love both of these authors. I have been hooked by both ever since I discovered their writings, and I follow their social media groups closely. This book did not disappoint. Sure, there are several questions that I have, a couple of times I went huh (which I won't get into because I do not want to offer any spoilers) and I hated the cliff hanger lol, but I cannot lie and say I didn't love the book, because I did. The twist on angels was new and fresh, even though that is part of my questions. The beginning and ending were the better parts, the middle was needed but sorta bogged a little. Kieran was confusing but relatable. Niz is BY FAR the best character of the book, love NIZ. For me, Bastian is a close second, always loved the crazy ones. The other men were good, but Steele gets on my nerves and as of right now, IMO, he doesn't belong, but we will see how that goes. I have lots of questions, but this was an excellent start to a new series and I cannot wait for the next book. Highly recommend
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Reviewed in the United States on February 21, 2024
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shark
Belleville, US
★★★★★ 4
fallen destiny? more like destined to fall in love
Format: Kindle
Kieran is an angel, but she doesn't have an affinity. Nothing angers her father more. If she doesn't find an affinity soon she will be cast to earth & have her wings removed. But she has the choice to become a fallen angel, wings turn black, & live her life on edge. Towards the end of the book things start to make sense. Gabe’s nickname for Kieran, Steele’a hatred, Bastian’s belief that Kieran is powerful. This book ended literally during a war? As one of her friends was injured, and admitted a bit secret? Talk about cliff hanger. The next book comes out August 5th.
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Reviewed in the United States on July 8, 2024
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Caylee T.
Grantham, US
★★★★★ 5
Well holy moly!
Format: Kindle
Holy moly that story definitely had me hooked! Kieran was definitely a character that I immediately adored. She has obviously had to deal with a butt load of too high expectations from her father (who is 🤬).. She has been helpless when it came to finding out her affinity with so many years of no answers & perceived failure. When Ronan, gives her a small inkling of hope that she be a Beast Tamer, she jumps into it. But again she doesn’t seem to fit. But when she runs into Gabe again, she ends up helping him & rethinking her life in Alfemir. And when the opportunity comes she decides leaving is the best option. But when Ronan demands he comes with her & then the random appearance of Bastian, she is feeling very overwhelmed. After she chooses to fall with them, they land on earth exactly where Gabe is located only to run into Steele who is a person that I was finding hard to like. After training, she eventually finds out she does have an affinity & it’s one that no longer exist & is incredibly powerful but also has a prophecy attached to it. I feel incredibly bad for her on she learns about the prophecy & Steele’s connection with it too. But that ending, with the battle scene & Niz….yeah definitely was not expecting that but hello I am all here for it too! Absolutely amazing start of a series & I for sure will be waiting for the next one to come out. Amazing job!
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Reviewed in the United States on September 26, 2024

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